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Science Fiction

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Science Fiction

The Substance

September 7, 2024
Directed by
Coralie Fargeat

A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.

new year's eve

capitalism

birthday

black market

identity

+23 more

Last Updated: November 3, 2025

Cast

Demi Moore as Elisabeth

Demi Moore

Elisabeth

Margaret Qualley as Sue

Margaret Qualley

Sue

Dennis Quaid as Harvey

Dennis Quaid

Harvey

Edward Hamilton-Clark as Fred

Edward Hamilton-Clark

Fred

Gore Abrams as Oliver

Gore Abrams

Oliver

Oscar Lesage as Troy

Oscar Lesage

Troy

Christian Erickson as Man at Diner

Christian Erickson

Man at Diner

Robin Greer as Male Nurse

Robin Greer

Male Nurse

Tom Morton as Doctor

Tom Morton

Doctor

Hugo Diego Garcia as Diego - Boyfriend

Hugo Diego Garcia

Diego - Boyfriend

Daniel Knight as Casting Director

Daniel Knight

Casting Director

Jonathon Carley as Assistant Casting Director

Jonathon Carley

Assistant Casting Director

Jiselle Henderkott as Girl Auditioning / New Year's Eve Show Dancer

Jiselle Henderkott

Girl Auditioning / New Year's Eve Show Dancer

Akil Wingate as TV Host

Akil Wingate

TV Host

Vincent Colombe as Man in Suit #1 - Harvey's Office

Vincent Colombe

Man in Suit #1 - Harvey's Office

The Substance Trailer #2 (2024) | Fandango at Home

The Substance Trailer #2 (2024) | Fandango at Home

Official Trailer #2

Official Trailer #2

The Substance Trailer #1 (2024)

The Substance Trailer #1 (2024)

Official Trailer

Official Trailer

Mark it in your calendar

Mark it in your calendar

The Substance Teaser Trailer (2024)

The Substance Teaser Trailer (2024)

Official Teaser

Official Teaser

Official Vertical Teaser

Official Vertical Teaser

"Especially not now..."

"Especially not now..."

"We got you just a little something..."

"We got you just a little something..."

Official Clip - Pretty Girls Should Always Smile

Official Clip - Pretty Girls Should Always Smile

Official Clip - Get Ready With Me

Official Clip - Get Ready With Me

Official Clip - I'd Like To Order

Official Clip - I'd Like To Order

The Substance (2024) - "I'm Sue"

The Substance (2024) - "I'm Sue"

Official Clip - Lucky Day

Official Clip - Lucky Day

To everyone who has gone out to see The Substance in cinemas…

To everyone who has gone out to see The Substance in cinemas…

Official Clip - Pump It Up With Sue

Official Clip - Pump It Up With Sue

On my way to see The Substance again 🧪

On my way to see The Substance again 🧪

Director Coralie Fargeat Dives Deep with Sean Evans on David Lynch & More

Director Coralie Fargeat Dives Deep with Sean Evans on David Lynch & More

Inside the Screenplay

Inside the Screenplay

In Conversation with Demi Moore & "Charlie's Angels"

In Conversation with Demi Moore & "Charlie's Angels"

Coralie Fargeat’s reaction on her Academy Award nomination for Best Director for The Substance

Coralie Fargeat’s reaction on her Academy Award nomination for Best Director for The Substance

Behind the Scenes

Making-Of Featurette

Making-Of Featurette

Q&A with Coralie Fargeat & Guillermo del Toro

Q&A with Coralie Fargeat & Guillermo del Toro

Tree’s up 🎄

In Conversation with THE SUBSTANCE Filmmaker Coralie Fargeat

In Conversation with THE SUBSTANCE Filmmaker Coralie Fargeat

Official Interview - Margaret Qualley

Official Interview - Margaret Qualley

Official Interview - Demi Moore at Cannes Film Festival

Official Interview - Demi Moore at Cannes Film Festival

THE SUBSTANCE - Coralie Fargeat rips beauty standards to gory shreds | MUBI Podcast

THE SUBSTANCE - Coralie Fargeat rips beauty standards to gory shreds | MUBI Podcast

Breaking Down THE SUBSTANCE's Shrimp Scene

Breaking Down THE SUBSTANCE's Shrimp Scene

The hype is real

The hype is real

Image Gallery

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